GHS-R1a signaling in the DMH and VMH contributes to food anticipatory activity
نویسندگان
چکیده
منابع مشابه
GHS-R1a constitutive activity and its physiological relevance
Abundant evidences have shown that ghrelin, by its binding to GHS-R1a, plays an important role for fundamental physiological functions. Increasing attention is given to the GHS-R1a unusually high constitutive activity and its contribution to downstream signaling and physiological processes. Here, we review recent lines of evidences showing that the interaction between ligand-binding pocket TM d...
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The gut hormone, ghrelin, is the only known peripherally derived orexigenic signal. It activates its centrally expressed receptor, the growth hormone secretagogue receptor (GHS-R1a), to stimulate food intake. The ghrelin signaling system has recently been suggested to play a key role at the interface of homeostatic control of appetite and the hedonic aspects of food intake, as a critical role f...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2013
ISSN: 0307-0565,1476-5497
DOI: 10.1038/ijo.2013.131